DES DES /ˌdɪ/

noun

1. () A potent estrogen used in medicine and in feed for livestock and poultry  ( diethylstilboestrol , stilbestrol , stilboestrol , DES , diethylstilbestrol )
   a potent estrogen used in medicine and in feed for livestock and poultry
   
2. Synthetic nonsteroid with the properties of estrogen; formerly used to treat menstrual problems but was found to be associated with vaginal cancers in the daughters of women so treated during pregnancy  ( DES , diethylstilbesterol , stilbesterol )
   synthetic nonsteroid with the properties of estrogen; formerly used to treat menstrual problems but was found to be associated with vaginal cancers in the daughters of women so treated during pregnancy
   

 DE DE /ˈdeɪ, də/

noun

1. A Mid-Atlantic state; one of the original 13 colonies  ( DE , Del. , Delaware , Diamond State , First State )
   a Mid-Atlantic state; one of the original 13 colonies