misfortune misfortune /mɪsˈfɔrtʃən/

noun

1. () Unnecessary and unforeseen trouble resulting from an unfortunate event  ( bad luck , misfortune )
   unnecessary and unforeseen trouble resulting from an unfortunate event
     The family faced a string of misfortunes, but they remained resilient.
   The family faced a string of misfortunes, but they remained resilient.
   
2. () An unfortunate state resulting from unfavorable outcomes  ( ill luck , tough luck , bad luck , misfortune )
   an unfortunate state resulting from unfavorable outcomes
     Despite his best efforts, misfortune seemed to follow him.
   Despite his best efforts, misfortune seemed to follow him.